Sepsis Clinical Guide

Sepsis is a serious systemic infection that can quickly lead to circulatory shock, organ failure and death if inappropriately treated. It is also a serious problem in hospitals throughout the US and the world. In 2013, 1.3 million people were admitted to US hospitals for sepsis (#1 cause of index admissions!) at a total cost to the US healthcare system of $23.7 billion dollars (#1 most expensive condition!). Over 250,000 people die of sepsis in the US every year, more than from prostate cancer, breast cancer and AIDS combined. Despite its large toll on public health, public awareness of this condition is poor and the quality of treatment is highly variable often due to late recognition and treatment.

In sepsis, time is of the essence. Successful treatment hinges on prompt recognition of symptoms, correct antibiotic administration, and hemodynamic stabilization. Lack of appropriate sepsis management knowledge at the bedside leads to delayed symptom recognition, serious complications, medical errors, increased treatment costs, and avoidable morbidity and mortality. For this reason, we created this app to provide busy health professionals with essential management information based on the latest practice guidelines in a format that is easily accessible at the point of care.

The Sepsis app features search, annotation, bookmarking functions and calculator support. All content is extensively referenced and footnoted where appropriate, and periodically updated. This app remains free of charge due to the generous sponsorship of Beckman Coulter.

Clinical topics covered in the Sepsis app include:

- The latest definitions and clinical guidelines including Sepsis-3 and the 2016 Surviving Sepsis Campaign (SSC) guidelines

- Epidemiology, risk factors and pathophysiology of sepsis and septic shock

- Common differentials and etiology, guidelines on performing appropriate H&P and workups

- Management of common causes including hospital-acquired pneumonia (HAP), ventilator-acquired pneumonia (VAP) and intra-abdominal infections

- Sepsis management bundles, early goal-directed therapy, hemodynamic management, adjunctive therapies, mechanical ventilation of sepsis-induced ARDS, and other essential management guidelines from the SSC and the American Thoracic Society (ATS)

- Antibiotic therapy including specific guidelines for the treatment of HAP from ATS and the Infectious Diseases Society of America (IDSA)

- Diagnosis and management of pediatric and neonatal sepsis including the management of pediatric fever, important differences from management of sepsis in adults, management of sepsis-induced persistent pulmonary hypertension of the newborn (PPHN), empiric antibiotic treatment recommendations for GBS infections, interventions in pediatric septic shock, and other pediatric-specific information

- Important calculators including the Sequential Organ Failure Assessment (SOFA), quick-SOFA, APACHE II, Multiple Organ Dysfunction Score (MODS), the Simplified Acute Physiology Score (SAPS) II, the National Early Warning Score (NEWS), the Clinical Pulmonary Infection (CPI) score, the Inferior Vena Cava Collapsibility Index, and others

- Drug administration information including antibacterial and antifungal antibiotics, adrenergic and other vasoactive agents, corticosteroids and diuretics

Recommended by:

- Top US doctors on HealthTap

- MDLinx.com

- imedicalapps.com

- The Russian Sepsis Forum (sepsisforum.ru)

- The ED Trauma Critical Care Blog (edtcc.com)

Sepsis adalah jangkitan sistemik serius yang cepat boleh membawa kepada kejutan peredaran darah, kegagalan organ dan kematian jika tidak sesuai dirawat. Ia juga merupakan satu masalah yang serius di hospital-hospital di seluruh Amerika Syarikat dan dunia. Pada tahun 2013, 1.3 juta orang telah dimasukkan ke hospital untuk US sepsis (# 1 punca kemasukan indeks!) Pada jumlah kos kepada sistem penjagaan kesihatan AS $ 23.7 bilion dolar (# 1 Keadaan yang paling mahal!). Lebih 250,000 orang mati kerana sepsis di Amerika Syarikat setiap tahun, lebih daripada kanser prostat, kanser payudara dan AIDS digabungkan. Walaupun tol yang besar ke atas kesihatan awam, kesedaran orang ramai terhadap keadaan ini adalah miskin dan kualiti rawatan adalah sangat berubah-ubah sering disebabkan oleh pengiktirafan lewat dan rawatan.

Dalam sepsis, masa adalah amat penting. Rawatan yang berjaya bergantung kepada pengiktirafan segera gejala, pentadbiran antibiotik betul, dan penstabilan hemodinamik. Kekurangan pengetahuan pengurusan sepsis sesuai di sisi katil itu membawa kepada pengiktirafan lambat gejala, komplikasi serius, kesilapan perubatan, kos rawatan meningkat, dan morbiditi dielakkan dan kematian. Atas sebab ini, kami mencipta aplikasi ini untuk menyediakan profesional kesihatan sibuk dengan pengurusan maklumat penting berdasarkan garis panduan amalan terbaru dalam format yang mudah diakses di tempat penjagaan.

Aplikasi Sepsis mempunyai carian, anotasi, fungsi bookmark dan sokongan kalkulator. Semua kandungan meluas dirujuk dan footnoted di mana sesuai, dan secara berkala dikemaskini. Aplikasi ini kekal percuma kerana penajaan murah hati Beckman Coulter.

topik klinikal dibincangkan dalam aplikasi Sepsis termasuk:

- Definisi terkini dan garis panduan klinikal termasuk Sepsis-3 dan 2016 masih hidup garis panduan Kempen Sepsis (SSC)

- Epidemiologi, faktor-faktor risiko dan pathophysiology sepsis dan kejutan septik

- perbezaan biasa dan etiologi, garis panduan kepada perlaksanaan sesuai H & P dan workups

- Pengurusan punca lazim termasuk hospital yang diperolehi pneumonia (HAP), ventilator yang diperolehi pneumonia (VAP) dan jangkitan intra-abdomen

- berkas pengurusan Sepsis, matlamat diarahkan awal terapi, pengurusan hemodinamik, terapi adjunctive, pengudaraan mekanikal ARDS sepsis disebabkan, dan garis panduan pengurusan penting lain dari SSC dan Thoracic Society Amerika (ATS)

- Rawatan antibiotik termasuk garis panduan khusus untuk rawatan HAP dari ATS dan Penyakit Berjangkit Society of America (IDSA)

- Diagnosis dan pengurusan sepsis pediatrik dan neonatal termasuk pengurusan demam pediatrik, perbezaan penting daripada pengurusan sepsis di kalangan orang dewasa, pengurusan sepsis yang disebabkan oleh tekanan darah tinggi pulmonari berterusan bayi yang baru lahir (PPHN), empiric cadangan rawatan antibiotik untuk jangkitan GBS, campur tangan dalam kejutan septik pediatrik, dan lain-lain maklumat pediatrik khusus

- kalkulator Penting termasuk Kegagalan Sequential Organ Taksiran (SOFA), cepat-SOFA, APACHE II, Berbilang Organ Disfungsi Skor (arena), yang Mudah akut Fisiologi Skor (SAPS) II, Negara Amaran Awal Skor (BERITA), Pulmonary Klinikal jangkitan (CPI) Perincian, Inferior Indeks Collapsibility Vena Cava, dan lain-lain

- Maklumat Pentadbiran Dadah termasuk antibakteria dan antibiotik antikulat, adrenergic dan ejen vasoactive lain, kortikosteroid dan diuretik

Disyorkan oleh:

- doktor Top AS pada HealthTap

- MDLinx.com

- imedicalapps.com

- Rusia Sepsis Forum (sepsisforum.ru)

- The ED Trauma Care kritikal Blog (edtcc.com)